Cemento-ossifying fibroma is classified as an osteogenic tumor, defined as a well -differentiated tumor, occasionally encapsulated, comprising fibrous tissue. Abstract. Introduction: Cemento-ossifying fibroma is a benign fibro-osseous maxillary tumor belonging to the same category as fibrous dysplasia and. Background: Cemento-Ossifying Fibroma (COF) is considered by most as relatively rare, benign, non-odontogenic neoplasm of the jaw bones and other.

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A clinical report M. In our case, the multilocular radiolucency seen was in the mandibular posterior region, but older age group involvement was noted. Open in a separate window. Radiographically, depending on the amount of cementum deposition, it may resemble fibrous dysplasia, cemento-osseous dysplasia, odontogenic cysts and tumors like keratocystic osskfying tumor, calcifying odontogenic cysts Gorlin cystsand calcifying epithelial odontogenic tumors Pindborg tumors.

Cemento-ossifying fibroma of the mandible

Other locations within the head and neck have been described 1. Clinical, radiographic and histopathologic features of Fibrooma and other fibro-osseous lesions are overlapping and may cause confusion in classification, diagnosis and treatment.

Occasionally bleeding occurred when he brushed his teeth. In the early stages, COF may appear as unilocular or multilocular radiolucent lesion and as the lesion matures, they may transform into a vibroma one, resulting in a lesion with mixed density.

Cemento-Ossifying Fibroma- A Case Report | OMICS International

Post-operative radiograph showing healed enucleated alveolar bony pattern. Teeth are often displaced by the growing mass. Abstract The concept of fibroosseous lesions of bone has evolved over the last several decades and now includes two major entities: Case Reports in Dentistry.

POF is a slowly progressing lesion, the growth of which is generally limited. The pathogenesis of this tumor is uncertain. Intraorally, the swelling was observed in the lower buccal vestibule leading to obliteration of the mucobuccal fold with respect to lower right molars and measured approximately 3cm cemenyo 4cm in size.


Computed tomography scan showing expansion of the buccal and lingual cortices of the mandible. De Vi Cente Rodriguez, S. Histopathological picture showing tightly cellular connective tissue stroma with abundant hyperchromatic fibroblasts and sparely collagen fibres along with scattered irregular shaped oszifying cementum like tissue.

It was found that COFs showed significant immune-reactivity for keratan sulphate, while intense immunostaining for chondroitinsulfate was observed in ossifying fibromas and fibrous dysplasias. The origin of cemento-ossifying fibroma is not clearly understood, in most of cases reported in literature have found to have history of trauma which is not osssifying in our case.

Cemento-ossifying fibroma of the mandible

ossifynig An interdisciplinary approach is required [ 14 ] to diagnose a COF from clinical, radiographic and microscopic features. However, these so-called cementicles are not from cementum but instead represent a dysmorphic product of this tumour analogous to the keratin pearls, which are a dysmorphic product of squamous cell carcinoma [ 13 ].

A clinicopathologic stidy of sixty-four cases.

The lesion was diagnosed as a cemento-ossifying fibroma. Computed tomography CT scan showed expansion of the buccal fibroms lingual cortical plates of the mandible [ Figure 3 ].

Home Publications Cemmento Register Contact. Indian J Dent Res ; J Indian Soc Periodontol. Digital panoramic radiograph taken revealed a well-defined multilocular radiolucent lesion in the right mandibular body ossifyingg extending up to the ramus Figure 2. The lesion appeared exophytic and nodular with irregular surface. Surgical procedure showing extracted tooth sockets.

Fibro-osseous lesions of the jaws. Giant cemento-ossifying fibroma—A case report and review of literature. Author information Article notes Copyright and License information Disclaimer.


It is a benign growth, considered fibrlma originate from the periodontal ligament and presents as a slow-growing lesion, but may cause deformity if left untreated.

Cemento-Ossifying Fibroma COF is considered by most as relatively rare, benign, non-odontogenic neoplasm of the jaw bones and other craniofacial bones characterized by replacement of normal bone by fibrous tissue and varying amounts of newly formed bone or cementum-like material, or both.

They are insensitive to radiotherapy and recurrences are uncommon. Subscribe to Table of Contents Alerts. Stern, Oral And Maxillofacial Pathology: Cemento-ossifying fibroma COF are rare, benign neoplasms that usually arise from the mandible or maxilla. The lesion was neither fluctuant nor did it blanch on pressure, but had a rubbery consistency. Based on radiological and histological findings, case was diagnosed as central cemento-ossifying fibroma. The lesion was seen extending beyond the lower border of the mandible with expansion and thinning of the cortical plates.

Patient also had a history of pus discharge from left ear, which resolved spontaneously. Imaging in the diagnosis of cemento-ossifying fibroma: Titinchi F, Morkel J.

IOPAR view showing external root resorption in relation to 35, 36 and 37 and mixed periapical radiolucency with radioopacification. No history of previous similar swelling, fibroa, or numbness could be elicited. A confirmatory diagnosis of peripheral cemento-ossifying fibroma is ossiying by histopathologic evaluation of biopsy specimens.